BDBM50437884 CHEMBL2407950

SMILES Cc1cc(ccn1)C(CC(c1ccc(Br)cc1)c1ccccc1C)N=O

InChI Key InChIKey=INISOYAKHGTHDU-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437884   

TargetG-protein coupled bile acid receptor 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataEC50:  740nMAssay Description:Agonist activity at recombinant mouse GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataEC50:  28nMAssay Description:Agonist activity at recombinant human GPBAR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50437884(CHEMBL2407950)
Affinity DataEC50:  500nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed