BDBM50436476 CHEMBL2397316

SMILES Cc1nc(NC(=O)C(C)(C)CC(F)(F)F)sc1-c1ccc(N)nc1

InChI Key InChIKey=UGTHQAXCCBBNQW-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50436476   

TargetPhosphatidylinositol 4-kinase beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 48nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
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TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetRibosomal protein S6 kinase alpha-4(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of MSK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PIK3C2B (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PIK3C2A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetSerine/threonine-protein kinase 17A(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

LigandBDBM50436476(CHEMBL2397316)Copy SMILESCopy InChI

Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of STK17A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL