BDBM50436000 CHEMBL2392179

SMILES COc1ccc(C(=O)Nc2cc(Br)cc3c2oc(cc3=O)C(O)=O)c(Cl)c1

InChI Key InChIKey=OHKLHXMRSPNFAH-UHFFFAOYSA-N

Data  1 KI  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50436000   

TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataEC50:  11nMAssay Description:Agonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 55(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataIC50: 2.17E+4nMAssay Description:Antagonist activity at human GPR55 expressed in CHO cells assessed as inhibition of lysophosphotidylinositol-induced beta-arrestin recruitment preinc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG protein-coupled receptor GPR35(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataEC50:  4.17E+3nMAssay Description:Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436000(CHEMBL2392179)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed