BDBM50434752 CHEMBL2385582

SMILES C1CN(CCO1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key InChIKey=SZVLDZCYMADNPG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50434752   

TargetTGF-beta receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50: 26nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50: 326nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50: 178nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed