BDBM50434748 CHEMBL2385600

SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cn[nH]c1

InChI Key InChIKey=IIYOBXCNRFSCBH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50434748   

TargetBone morphogenetic protein receptor type-1B(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 102nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein 4(Mouse)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 94nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 52nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 44nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 41nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 24nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 16nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 110nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed