BDBM50434359 CHEMBL2386769::US9446044, 80

SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(cc4)C(F)(F)F)c3c2s1

InChI Key InChIKey=NFPDLDFOSLPKHQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50434359   

LigandPNGBDBM50434359(CHEMBL2386769 | US9446044, 80)
Affinity DataIC50: 18.3nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50434359(CHEMBL2386769 | US9446044, 80)
Affinity DataIC50: 25.2nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50434359(CHEMBL2386769 | US9446044, 80)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434359(CHEMBL2386769 | US9446044, 80)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed