BDBM50434272 CHEMBL1242297

SMILES Cc1cc(-c2ccc(\C=C3/S\C(NC3=O)=N/c3ccc(Cl)c(c3)C(O)=O)o2)c(cc1C)[N+]([O-])=O

InChI Key InChIKey=RTHRCOIONCZINZ-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50434272   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  8.00E+3nMAssay Description:Activation of human recombinant AMPK alpha1 subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  8.00E+3nMAssay Description:Activation of human recombinant AMPK alpha1 (1 to 394 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL using SAMS peptide after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  1.20E+4nMAssay Description:Activation of human recombinant AMPK alpha2 expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL using SAMS peptide after 10 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  300nMAssay Description:Activation of human recombinant AMPK alpha1/beta1/gamma1 expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL using SAMS peptide after 10 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  300nMAssay Description:Activation of recombinant AMPK alpha2beta1gamma1 (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  9.60E+3nMAssay Description:Activation of recombinant AMPK alpha1 (1 to 394) (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  9.00E+3nMAssay Description:Activation of human AMPK alpha1 (1 to 394) expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  1.20E+4nMAssay Description:Activation of human AMPK alpha2 (1 to 398) expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  300nMAssay Description:Activation of recombinant human AMPK alpha1/beta1/gamma1expressed in Escherichia coli BL21-codon plus(DE3)-RIL using SAMS peptide as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed