BDBM50434022 CHEMBL2381188::US8598155, 52

SMILES Cc1nc(-c2cnn(C)c2-c2ccc(cc2)C(F)(F)F)c2c(ncnn12)N1CC(F)C1

InChI Key InChIKey=NXNPDXUSIAPGFQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434022   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

US Patent

LigandBDBM50434022(CHEMBL2381188 | US8598155, 52)Copy SMILESCopy InChI

Affinity DataIC50: 0.633nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2014
Entry Details
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TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50434022(CHEMBL2381188 | US8598155, 52)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE11 (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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