BDBM50431947 CHEMBL2348091
SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
InChI Key InChIKey=FXCKSJPZDBQRLO-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50431947
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant MMP-14 using fluorescence peptide matrix as substrate after 45 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant ADAMTS-4 using interglobular domain peptide of aggrecan after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Bovine)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Ex vivo inhibition of ADAMTS-5-mediated aggrecan degradation in IL-1-stimulated bovine cartilage explantMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of MMP14 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 13(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ADAMTS-13 (unknown origin)More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair