BDBM50431176 CHEMBL2332556

SMILES CN1CC(O)(OC2CCCCC12)c1ccc(cc1)-c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=JMXQDJTXESQDMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50431176   

TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50431176(CHEMBL2332556)
Affinity DataIC50: 210nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as inhibition of [3H] FPP conversion to squalene after 10 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50431176(CHEMBL2332556)
Affinity DataIC50: 210nMAssay Description:Inhibition of SQS in rat microsomes using [3H]-FPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed