BDBM50431030 CHEMBL379849

SMILES Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O

InChI Key InChIKey=NIVYQYSNRUIFIF-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50431030   

TargetMAP kinase-activated protein kinase 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant MAPKAPK2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of recombinant MAPK14 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant KDR (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek1(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of recombinant MEK1 (unknown origin) by cascade reaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant RAF1 (unknown origin) by cascade reaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant RPS6K1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of recombinant IKBKB (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant AKT2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant AKT1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed