BDBM50429811 CHEMBL2337670

SMILES CCOC(=O)C(=O)N(Cc1ccccc1)c1ccc2OC[C@H](COc3ccc(cc3)C(N)=[NH2+])Oc2c1

InChI Key InChIKey=DYUYSOFSDYVVJJ-UHFFFAOYSA-O

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429811   

TargetIntegrin alpha-V/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataKi:  78nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429811(CHEMBL2337670)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed