BDBM50429807 CHEMBL2337674

SMILES NC(=N)c1ccc(OC[C@H]2COc3ccc(cc3O2)N(Cc2ccccc2)C(=O)C(O)=O)cc1

InChI Key InChIKey=WINLUFCVTCWULP-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429807   

TargetIntegrin alpha-V/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataKi:  266nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50429807(CHEMBL2337674)
Affinity DataKi:  5.08E+3nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2222 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed