BDBM50429711 CHEMBL2336323::US9102670, 1dh

SMILES CNC(=O)c1cc(ccc1OC(F)F)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

InChI Key InChIKey=PUQKNADZOBNSOT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429711   

TargetSerine/threonine-protein kinase mTOR(Human)
Kudos Pharmaceuticals

US Patent

LigandBDBM50429711(CHEMBL2336323 | US9102670, 1dh)Copy SMILESCopy InChI

Affinity DataIC50: 40nMT: 2°CAssay Description:The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/4/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50429711(CHEMBL2336323 | US9102670, 1dh)Copy SMILESCopy InChI

Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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