BDBM50429653 CHEMBL2334978

SMILES CNc1cccc(n1)-c1c(NC(=O)[C@@H]2C[C@H]2C)snc1-c1ccc2nn(C)cc2c1

InChI Key InChIKey=XFENZAWQSSSCNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429653   

TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429653(CHEMBL2334978)
Affinity DataIC50: 1.59E+3nMAssay Description:Negative allosteric modulation of human recombinant mGlu1 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429653(CHEMBL2334978)
Affinity DataIC50: 62nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed