BDBM50429362 CHEMBL2336300

SMILES Cc1ccc2nc(c(NC3CCCCC3)n2c1)-c1ccc(OCCCNC(=O)Nc2ccc(cc2)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=GVIBHEMBVKBBBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429362   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50429362(CHEMBL2336300)
Affinity DataIC50: 192nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50429362(CHEMBL2336300)
Affinity DataIC50: 189nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed