BDBM50429070 CHEMBL2335742

SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1

InChI Key InChIKey=WQHNUCLXRFMSFN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50429070   

TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 27nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 46nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 42nMAssay Description:Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed