BDBM50427637 CHEMBL2323502

SMILES COc1ccc2n(cc(CC(=O)NS(=O)(=O)c3ccc(cc3)C#N)c2c1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=ZEYXTYZWOKTSJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427637   

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427637(CHEMBL2323502)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427637(CHEMBL2323502)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed