BDBM50427066 CHEMBL2322888

SMILES Cc1c(Cl)c(nn1CC(=O)N1CCN(CC1)c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=HTYBEXPZARGDNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427066   

TargetC-C chemokine receptor type 1(Human)
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427066(CHEMBL2322888)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3/MIP-1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427066(CHEMBL2322888)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3/MIP-1alpha-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Chemocentryx

Curated by ChEMBL
LigandPNGBDBM50427066(CHEMBL2322888)
Affinity DataIC50: 307nMAssay Description:Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed