BDBM50426436 CHEMBL2322369

SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)N1CCNCC1

InChI Key InChIKey=XXSXHAXCDDVVBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426436   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426436(CHEMBL2322369)
Affinity DataIC50: 870nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetFatty acid synthase(Rat)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426436(CHEMBL2322369)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426436(CHEMBL2322369)
Affinity DataIC50: 870nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426436(CHEMBL2322369)
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent