BDBM50426340 CHEMBL2321943

SMILES COc1cc2N(O)C(=O)[C@@H](N)Cc2cc1Oc1ccccc1

InChI Key InChIKey=HAJSIZYRDXXXND-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426340   

TargetKynurenine--oxoglutarate transaminase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50: 37nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataKi:  1.70nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed