BDBM50425806 CHEMBL2316907

SMILES OC(=O)c1cc2c(C#Cc3ccc(OC(F)(F)F)cc3)c(oc2cc1O)-c1ccccc1

InChI Key InChIKey=CMOKPKRDZUEWNH-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50425806   

TargetDual specificity protein phosphatase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of TCPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LYP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CD45 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase gamma(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PTPgamma (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of FAP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HEPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLaforin(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Laforin (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LMWPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LAR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed