BDBM50425002 CHEMBL2312191

SMILES CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)C(=O)N2CCOCC2)ncc1C#N

InChI Key InChIKey=UFUGKBGESCNADR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50425002   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  43nMAssay Description:Inhibition of CDK9/Cyclin T (1 to 330 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  43nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  147nMAssay Description:Inhibition of CDK2/Cyclin A (174 to 432 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  199nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  205nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50425002(CHEMBL2312191)
Affinity DataKi:  1.87E+3nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed