BDBM50424963 CHEMBL2316152::US9409845, Table 1, Compound 13: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-methoxybenzylidene)cyclohexanone

SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3OC)C2=O)c1

InChI Key InChIKey=UFXSXKGMRKSRAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424963   

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandPNGBDBM50424963(CHEMBL2316152 | US9409845, Table 1, Compound 13: (...)
Affinity DataIC50: 2.09E+4nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandPNGBDBM50424963(CHEMBL2316152 | US9409845, Table 1, Compound 13: (...)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed