BDBM50424953 CHEMBL2315819

SMILES CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)CC(O)=O)cc1C(F)(F)F

InChI Key InChIKey=KSSHDSRUZZMQAH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424953   

TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424953(CHEMBL2315819)
Affinity DataIC50: 95nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed