BDBM50424947 CHEMBL2315820
SMILES C[C@](N)(CC(O)=O)c1nc(c[nH]1)-c1ccc(OCc2ccc(cc2)-c2ccccc2)c(c1)C(F)(F)F
InChI Key InChIKey=FDNAXNKZGRCNLU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50424947
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair