BDBM50424947 CHEMBL2315820

SMILES C[C@](N)(CC(O)=O)c1nc(c[nH]1)-c1ccc(OCc2ccc(cc2)-c2ccccc2)c(c1)C(F)(F)F

InChI Key InChIKey=FDNAXNKZGRCNLU-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424947   

TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataIC50: 82nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in HEK293T cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals Incorporated (Currently Glaxosmithkline)

Curated by ChEMBL
LigandPNGBDBM50424947(CHEMBL2315820)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293T cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed