BDBM50423732 CHEMBL590389

SMILES CCc1cc(F)cc(C)c1C(=O)N[C@@H](Cc1ccc(cc1)N1CCC(CNc2ccccn2)CC1)C(O)=O

InChI Key InChIKey=ZMCITDRAZLHOJT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50423732   

TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50: 614nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50: 21nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed