BDBM50423721 CHEMBL595105

SMILES Cc1ccnc(NCC2CCN(CC2)c2ccc(CC(NC(=O)c3c(C)cc(C)cc3C)C(O)=O)cc2)c1

InChI Key InChIKey=RJFWKMUAMBANKC-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50423721   

TargetIntegrin alpha-5(Human)
Shire Orphan Therapies

US Patent
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 100nMpH: 9.6 T: 2°CAssay Description:Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

TargetIntegrin alpha-IIb(Human)
Shire Orphan Therapies

US Patent
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 1.00E+3nMpH: 9.6 T: 2°CAssay Description:Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

TargetIntegrin alpha-IIb/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 84nMAssay Description:Binding affinity to integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 84nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50423721(CHEMBL595105)
Affinity DataIC50: 69nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed