BDBM50421700 CHEMBL5289965

SMILES CS(=O)(=O)n1cc(COc2ccc3[nH]ccc3c2)c2cc(ccc12)C(=O)OCc1cc([nH]c(=O)c1)C#N

InChI Key InChIKey=ZXWIGRDUTDZBSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421700   

TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421700(CHEMBL5289965)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421700(CHEMBL5289965)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421700(CHEMBL5289965)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO2-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421700(CHEMBL5289965)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO3-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed