BDBM50421197 CHEMBL2087286

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccc(F)c(OCC(O)=O)c2)cc1)Cc1cc(F)cc(F)c1

InChI Key InChIKey=SUMDKKPJNURZEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421197   

TargetGlucocorticoid receptor(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421197(CHEMBL2087286)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421197(CHEMBL2087286)
Affinity DataIC50: 432nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in GRAF cells assessed as inhibition of dexamethasone-induced alkaline phosphatase exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421197(CHEMBL2087286)
Affinity DataIC50: 1.88E+3nMAssay Description:Antagonist activity at glucocorticoid receptor in rat hepatocytes assessed as inhibition of dexamethasone-induced trypsine aminotransferase expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed