BDBM50420670 CHEMBL2087064

SMILES CC(C)c1ccc(C)cc1NC(=O)CCCCCCCc1ccccc1

InChI Key InChIKey=ZIJWWPDYSCPZJK-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50420670   

TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420670(CHEMBL2087064)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rat TRPA1 expressed in HEK293 cells assessed as reduction in 100 uM allyl isothiocyanate-stimulated increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420670(CHEMBL2087064)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420670(CHEMBL2087064)
Affinity DataIC50: 300nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420670(CHEMBL2087064)
Affinity DataEC50:  800nMAssay Description:Activation of rat TRPA1 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed