BDBM50418866 CHEMBL1801371

SMILES CCn1c(CC(=O)NCc2ccc(F)c(F)c2F)c(C)nc1-c1ccccc1

InChI Key InChIKey=USMUJOYBPMHEPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418866   

TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418866(CHEMBL1801371)
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418866(CHEMBL1801371)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed