BDBM50417616 CHEMBL1645403

SMILES COc1ncc(cc1-c1ccc(cc1)[C@@H](C)NS(=O)(=O)c1cn(C)nc1C(F)(F)F)C#N

InChI Key InChIKey=QSPPOHUPKZMCQN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50417616   

TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417616(CHEMBL1645403)
Affinity DataEC50:  12.6nMAssay Description:Binding affinity to human recombinant GR by competition ligand binding fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417616(CHEMBL1645403)
Affinity DataEC50:  100nMAssay Description:Antagonist activity at human GR DNA binding domain transfected in CHO cells co-transfected with MMTV-luciferase gene assessed as inhibition of cortis...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417616(CHEMBL1645403)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human MR ligand binding domain transfected in CHO cells co-transfected with MMTV-luciferase gene assessed as inhibition of cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417616(CHEMBL1645403)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to human recombinant PR by competition ligand binding fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed