BDBM50417253 CHEMBL1271989

SMILES COc1ccc(NC(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)cc1

InChI Key InChIKey=XKPPTLZEMIKHSJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417253   

TargetOrexin receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417253(CHEMBL1271989)
Affinity DataKi:  200nMAssay Description:Antagonist activity against human orexin 2 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417253(CHEMBL1271989)
Affinity DataKi: >1.58E+4nMAssay Description:Antagonist activity against human orexin 1 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed