BDBM50416668 CHEMBL1222552

SMILES C1CN(CCN1)C1=Cc2ccccc2Cn2ccnc12

InChI Key InChIKey=NSRMKMSTPLJNHM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50416668   

TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  0.631nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in CHO cells by FLPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at human adrenergic Alpha-1B receptor assessed as intracellular calcium luminescence by cell based aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  3.98nMAssay Description:Antagonist activity at human adrenergic alpha1A receptor assessed as intracellular calcium luminescence by cell based aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  7.94nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK cells assessed as intracellular calcium luminescence by aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  19.9nMAssay Description:Antagonist activity at human 5HT2C receptor expressed in human SHSY5Y cells by FLPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416668(CHEMBL1222552)
Affinity DataKi:  316nMAssay Description:Antagonist activity at human 5HT2B receptor expressed in human SHSY5Y cells by FLPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed