BDBM50415892 CHEMBL1094411

SMILES Cc1nc(-c2ccccc2)n(C)c1CC(=O)NCc1ccc(F)cc1Cl

InChI Key InChIKey=OXEPSZPAOYMVFH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50415892   

TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415892(CHEMBL1094411)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415892(CHEMBL1094411)
Affinity DataIC50: 251nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415892(CHEMBL1094411)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed