BDBM50414986 CHEMBL568522

SMILES CC1(C)Oc2c(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccnc(N)c3)cccc2C=C1

InChI Key InChIKey=QCIHJSOOSHZRET-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414986   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50414986(CHEMBL568522)Copy SMILESCopy InChI

Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiologyMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetC-C chemokine receptor type 8(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50414986(CHEMBL568522)Copy SMILESCopy InChI

Affinity DataIC50: 5.62nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL