BDBM50414957 CHEMBL429436

SMILES Clc1ccc(cc1)C(=O)N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1

InChI Key InChIKey=RGZNEXHZUKHBNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50414957   

TargetC-C chemokine receptor type 8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 81.3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 19.1nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50414957(CHEMBL429436)
Affinity DataIC50: 603nMAssay Description:Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed