BDBM50410179 CHEMBL2096800
SMILES CC[C@@H](C)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)C(C)(C)NC(=O)CNC(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)C(C)C)C(C)C)C(=O)NC(C)(C)C(=O)N[C@H]([C@H](C)OCc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)NC(C)(C)C(=O)N[C@H](C(C)C)C(=O)N[C@H]([C@H](C)CC)C(=O)NC(C)(C)C(=O)OC
InChI Key InChIKey=XDMXMEOPXRRXDP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50410179
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against Gamma-secretase from APP-transfected CHO cellsMore data for this Ligand-Target Pair