BDBM50409216 CHEMBL150701

SMILES C(Cc1cnc[nH]1)C1CCNCC1

InChI Key InChIKey=XSOYKCANSOSZRB-UHFFFAOYSA-N

Data  4 KI  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50409216   

TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKd:  3.98nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataEC50: <1.00E+4nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataEC50:  13nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataEC50:  13nMAssay Description:Inhibition of cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-NR-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cells by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKi:  20nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409216(CHEMBL150701)
Affinity DataKi:  371nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed