BDBM50408218 CHEMBL4163771

SMILES Cc1ccnc(OCc2ccc(F)cc2)c1C(=O)NC1CCCCCC1

InChI Key InChIKey=FQBDLLQDJPGLMU-UHFFFAOYSA-N

Data  2 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50408218   

TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  229nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataKi:  131nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed