BDBM50406002 CHEMBL18912

SMILES CC(=O)Nc1ccc(Cc2cnc(N)nc2N)cc1[N+]([O-])=O

InChI Key InChIKey=AKHBBXPUWYDYHT-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50406002   

TargetDihydrofolate reductase(Escherichia coli)
Beijing Medical University

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  107nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Beijing Medical University

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  107nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coli (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Salmonella typhi)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  107nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Beijing Medical University

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  107nMAssay Description:Compound is evaluated for the inhibition of dihydrofolate reductase from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  6.92E+3nMAssay Description:Inhibition of dihydrofolate reductase from bovine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  4.57E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  4.57E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  4.57E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed