BDBM50405632 CHEMBL5278968

SMILES COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ccc(cc3)C(=O)NO)cc2n1

InChI Key InChIKey=PIANUSMCKHEMFQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50405632   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 19nMAssay Description:Inhibition of human PI3Kalpha by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 54nMAssay Description:Inhibition of human PI3Kbeta by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 39nMAssay Description:Inhibition of human PI3Kdelta by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human HDAC1 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC2 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC6 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human HDAC10 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human HDAC11 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed