BDBM50405529 CHEMBL4650909

SMILES C(C1CSC2(CCCCC2)S1)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=ZAOXCWMNIYUNPJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50405529   

TargetSigma intracellular receptor 2(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50405529(CHEMBL4650909)
Affinity DataKi:  5nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50405529(CHEMBL4650909)
Affinity DataKi:  12nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50405529(CHEMBL4650909)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor expressed in rat liver membranes assessed as inhibition constant incubated for 120 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50405529(CHEMBL4650909)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]pentazocine from sigma 1 receptor expressed in guinea pig brain membranes assessed as inhibition constant incubated for 150 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed