BDBM50405441 CHEMBL5286125

SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F

InChI Key InChIKey=MNFXHOXNYLMXRT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50405441   

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50405441(CHEMBL5286125)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Nav1.7 in inactivated condition by manual patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50405441(CHEMBL5286125)
Affinity DataIC50: 52nMAssay Description:Inhibition of human Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50405441(CHEMBL5286125)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mouse Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50405441(CHEMBL5286125)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50405441(CHEMBL5286125)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Nav1.5/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In DepthDetails
PubMed