BDBM50404382 CHEMBL5274757

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCOc1ccc(Oc3ccc(cc3)N(Cc3ccccc3)C(=O)CCl)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=CMXZJNKISXRUIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50404382   

TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404382(CHEMBL5274757)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant RNF4 incubated for 30 mins by SDS-PAGE based densitometryMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404382(CHEMBL5274757)
Affinity DataIC50: 540nMAssay Description:Binding affinity to RNF4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50404382(CHEMBL5274757)
Affinity DataIC50: 540nMAssay Description:Inhibition of IA-rhodamine-labeled human RNF4 preincubated for 30 mins followed by IA-rhodamine addition for 1 hr by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed