BDBM50403059 CHEMBL2216829::US9505766, 64

SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)NC(C)(C)C)n(CCCO)c2ncnc(N)c12

InChI Key InChIKey=SVXJIKFFHBDTNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403059   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50403059(CHEMBL2216829 | US9505766, 64)
Affinity DataIC50: 4.5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Covalution Pharma

Curated by ChEMBL
LigandPNGBDBM50403059(CHEMBL2216829 | US9505766, 64)
Affinity DataIC50: 4nMAssay Description:Inhibition of RSK2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed