BDBM50401906 CHEMBL2207187

SMILES Fc1cccc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)c1

InChI Key InChIKey=URECOWLJWSLQCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401906   

TargetSerine/threonine-protein kinase TBK1(Mouse)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401906(CHEMBL2207187)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of TBK1-mediated RANTES release in LPS-stimulated mouse RAW264.7 cells compound incubated for 30 mins prior LPS challenge measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401906(CHEMBL2207187)
Affinity DataIC50: 580nMAssay Description:Inhibition of PDK1 by radiometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401906(CHEMBL2207187)
Affinity DataIC50: 8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed