BDBM50401363 CHEMBL2205827

SMILES COc1ccc(CN2C3C4C5C6C4C2(O)C2C6CC5C32)cc1OC

InChI Key InChIKey=MGYAQEPRQTVZOM-UHFFFAOYSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50401363   

TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  228nMAssay Description:Displacement of [3H](+)-pentazocine from rat brain sigma1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity to alpha2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.23E+3nMAssay Description:Binding affinity to M4 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.27E+3nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  1.73E+3nMAssay Description:Binding affinity to M3 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  2.77E+3nMAssay Description:Binding affinity to alpha1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  3.58E+3nMAssay Description:Inhibition of histamine H2 receptor (unknown origin) by PDSP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  3.58E+3nMAssay Description:Binding affinity to Histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  3.65E+3nMAssay Description:Binding affinity to 5-HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  4.16E+3nMAssay Description:Binding affinity to M5 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  4.16E+3nMAssay Description:Binding affinity to 5-HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  4.42E+3nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi:  4.61E+3nMAssay Description:Binding affinity to M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50401363(CHEMBL2205827)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to alpha1A adrenergicMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed