BDBM50401328 CHEMBL2087239

SMILES COc1c(C(=O)NC2CCN(CC2)C(=O)CO)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21

InChI Key InChIKey=MBNHXHOKPNBCPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50401328   

TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed